Science Cafe, February 24, 2026: Sleep

with Abhilash Lakshman, PhD, Shafer Lab

With every rotation of the earth, we cycle from the “unrecorded fantasies of solitary dreaming, to the collective fantasy of daily social and commercial life.”
 
What determines when and how much we sleep?  How does light influence sleep timing and levels?
 
Join us as we talk about how tiny insects help us answer these questions.

A painless operation- what can fruitflies teach us about pain pathways?

Research in the Tracey laboratory aims to understand the general principles that govern the specification and function of neuronal circuits. We study this problem using the fruitfly Drosophila melanogaster whose relatively simplified nervous system must perform many of the same computations that are carried out by our own. Despite its simplified brain, Drosophila perform an array of complex behaviors. Powerful genetic tools of Drosophila enable the dissection of neural circuits with a precision that is not matched in any other model system. Genetically encoded calcium sensors allow us to measure the neuronal activity of identified neurons while neuronal silencers and activators allow us to determine the behavioral consequences of the same activity. We are using the fly model to identify circuits and genes that function in nociception which is the sensory input involved in pain signaling. In addition, we are attempting to identify the molecules that are used in neurosensory mechanotransduction which underlies our sense of touch.

Speaker

Dan Tracey PhD
Associate Professor
Department of Biology, IUB